- Simple pressure and vacuum control
Precise pressure control is achieved directly through manual knob operation - Stable flow control
Combined with flow sensors, long-term controlled fluid perfusion is achieved. - Intuitive user interface
Manual operation or computer software operation to control pressure and flow - Portable, compact and independent
Miniature table size with built-in pressure source without any external pressure source. - Cobalt pressure pumps are available in 2 versions
Cobalt with a pressure range of 0 to 2 bar and a Cobalt-Dual with a pressure range of -700 to 1000 mbar.
Key features:
Premium pressure and vacuum control
Cobalt automatic microfluidic pressure pumps are available in 2 versions. When combined with flow sensors, both versions allow gas or flow control.
- Positive pressure control from 0 to 2000 mbar
- •Positive pressure and vacuum control from -700 to 1000 mbar
Cobalt technology improves the performance of microfluidic instruments, making them easier to use. Cobalt automatic microfluidic pressure pumps are designed based on the OB1 MK4 controller and use piezoelectric technology-based pressure regulation.
Unique performance compared to syringe or peristaltic pumps
Elveflow Cobalt automatic microfluidic pumps offer superior fluid drive performance compared to microfluidic syringe pumps or peristaltic pumps. Since it does not use mechanical components to generate pressure, the Cobalt generates high-precision gas pressure to drive the liquid flow smoothly.
When used in combination with MFS flow sensors, Cobalt pressure pumps enable powerful liquid flow control:
- High stability (water test) over 0-5mL/min flow range: 3.5nL/min (MFS2) to 1μL/min (MFS5)
- High accuracy (water test) over 0-5mL/min flow range: 20nL/min (MFS2) to 10μL/min (MFS5)
Automatic and stand-alone instrumentation: no need for an external air source and vacuum pump for air supply
The Cobalt Automatic Microfluidic Pressure Pump is the ideal device for your bench. It has a built-in pressure source (and vacuum source), so there is no need for an external air compressor or gas supply from a cylinder or vacuum pump in the laboratory. At the same time, its design minimizes vibration and noise.
Embedded user interface
With full control of Cobalt’s intuitive hardware without the need for external software, any user can manually operate the pressure drive and flow control of liquid flow.
A basic example: microfluidic chip priming
Applications:
Cobalt pressure pumps are premium microfluidic control instruments with a wide range of applications:
- On-chip lab development
- Benchmarking or characterization (chips, sensors, filters, etc.)
- Mechanobiology (Cell Restriction, Tissue Engineering, etc.)
- Cell perfusion
Specifications
Hardware parameters of both versions of Cobalt
Comparison of interface and software functions between manual operation and computer software
For the Cobalt Automatic Microfluidic Pressure Pump product brochure, please click here to download.
Typical applications for cell compression
Onal S, Alkaisi MM, Nock V (2023) Application of sequential cyclic compression on cancer cells in a flexible microdevice. PLoS ONE 18(1): e0279896. https://doi.org/10.1371/journal.pone.0279896
Fang, Xu, Pudi Wang, Feng Lin, Jianyong Huang, Jing Fang, and Chunyang Xiong. 2022. “Pneumatic Cell Stretching Chip to Generate Uniaxial Strain Using an Elastomeric Membrane with Ridge Structure” Chemosensors 10, no. 8: 302. https://doi.org/10.3390/chemosensors10080302
Onal Sevgi, Alkaisi Maan M., Nock Volker, A Flexible Microdevice for Mechanical Cell Stimulation and Compression in Microfluidic Settings, Frontiers in Physics , 2021.9, DOI=10.3389/fphy.2021.654918.